These proteins crowd pathways associated with immunological, neurological and cardiomyopathy disorders.
Proteins with domain-altering SNPs crowd cellular pathways involved in neurological, and immunological diseases, as well as in cancers such as the pancreatic cancer.
Broader cellular constraints such as regulation, protein crowding, pathway enzyme synthesis requirements, and pathway-throughput limits underlie these differences [ 17, 26, 27].
Its bookings are top-notch, and its location -- around a handsome bandshell, with the never-too-crowded pathways of Prospect Park on one side and the stately town houses of Park Slope on the other -- is ideal.
Negative impacts may also follow social and psychosocial pathways, as crowded conditions lead to family arguments and remove householders' sense of privacy and control.
And third, ants become more uniform when their pathways get more crowded.
The floor was so crowded that two people couldn't walk down the pathways side by side.
It, however, can also be distracting, if the pathway map gets too large, and therefore, too crowded.
Although there is similarity in the morphologies of aggregates identified in vitro and in vivo, it is important to note that the crowded cellular environment affects Htt aggregate species and the aggregation pathway itself in vivo.
Further, during the Tox21 Data Challenge 2014 [27], the development of computational models which can predict the interference of these chemicals in the two groups of pathways was crowd-sourced to researchers across the globe.
