Sentence examples for crossfire effect from inspiring English sources
The resulting crossfire effect circumvents any need for targeting all malignant cells and reduces the impact of low tumor penetration and heterogeneous antigen localization and therefore gives better tumor response [9].
Aiming to create a trap for Norreys' army, the Spanish had smoothed the ground on their right in order to funnel English units and draw Norrey's troops into an engagement area where a crossfire effect could be created.
Thus, complete responders may still derive benefit from the crossfire effect.
Moreover, because of the crossfire effect of radiation therapy, radioiodine can kill not only the NIS-expressing cells but also adjacent tumor cells [4].
Another advantage of RIT is the crossfire effect, which means that nontargeted cells are irradiated due to radiolabeled antibody uptake by surrounding cells.
This so-called crossfire effect can thus overcome heterogeneity of antigen expression, as the radiation destroys the antigen-negative cells as well.
The therapeutic activity of monoclonal antibodies (mAb) may be improved by arming them with additional effector mechanisms [1] such as ionizing radiation that kills neighboring untargeted tumor cells by bystander and/or radiation crossfire effects [2].
The relatively long range of β-particles causes energy disposition in neighboring non-targeted cells, known as the crossfire-effect.
Even though the 99mTc-MAA gamma radiation is smeared out, the homogenising effect of crossfire between microspheres will not smooth heterogeneity at this scale (the aim in treating tumour tissue, but unwanted in normal liver parenchyma), as the mean range of the 90Y beta radiation is only 2.5 mm.
One advantage of using beta particles to kill tumor cells is that their path range of up to 5 mm results in a large number of cells being penetrated by each electron, leading to a cumulative "bystander effect" due to crossfire from neighboring labeled cells.
Cooper is expert at detailing the effects of emotional crossfire.
