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Gene information is not readily available for spots, so it is harder to correlate or cross-validate expression profiles with gene annotations.
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Sections obtained from other control and ablated mice of comparable ages were also used for double-labelling studies to cross-validate the developmental patterns of expression of lacZ and HSV-TK reporters in GPT neurons.
For the highest-scoring transcription factors we cross-validated the expression pattern by looking for the number of corresponding tags in the LongSAGE libraries.
This concept was better visualized by cross-validating our expression data with a subset of canonical EZH2-regulated targets as identified by a previously reported EZH2 chromatin immunoprecipitation-sequencing (ChIP-seq) dataset in a different cell line [ 35], generated using an antibody that, according to our data, recognizes both the EZH2α and EZH2β isoforms.
Using their expression as a training set to cross-validate the diagnosis demonstrated 73% sensitivity and 77% specificity, and testing the prediction on an independent dataset (18 cancer and 17 non-cancer cases) showed similar 78% sensitivity and 65% specificity.
We have collected and analyzed both gene expression and proteomic data in order to cross-validate predictions based on different types of data and evaluate the utility of this approach to integrative data analysis.
To cross-validate and extend our initial findings, we sought to compare the expression profiles of these cell lines using an alternative microarray platform.
CVI served to cross-validate our results of model comparison.
To cross-validate, we halved the sample at random.
We compare different ways to cross-validate predictions from neuroimaging.
To cross-validate the enrichment of sugar-binding and sensory perception of sound categories in WBC, we have performed enrichment analysis in DAVID using the 'Tissue of Expression' annotation option (see Section 2).
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