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A consequence of this cross regulation is that, for instance, infection with an extracellular pathogen requiring a Th2 response may inhibit a Th1 response required for control of a simultaneous intracellular pathogen.
In addition, poorly buffered motifs are abundant and the TFs cross regulation is less extreme.
Both the difference in gene expression level and the cross-regulation are likely the molecular determinants of unequal genetic redundancy of RACK1 genes in regulating plant development.
Both the difference in RACK1 gene expression level and the cross-regulation are likely the molecular determinants of their unequal genetic redundancy.
These results suggest that, despite the tissue- and developmental stage-specific expression of different DUSPs, a significant degree of functional overlap and cross-regulation are certainly conceivable within the DUSP family.
We provide evidence that the difference in the gene expression level and the cross-regulation are likely the molecular determinants of unequal genetic redundancy of RACK1 genes in regulating plant development.
Because MOR-NMDAR cross-regulation is a redox-regulated process that depends on NO and zinc metabolism (51, 54), in wild-type mice, the inhibition of NOS enhanced morphine antinociception and prevented NMDA from reducing the antinociceptive capacity of morphine; however, this approach was not effective in the σ1R−/− mice (Fig. 8A).
New crossing points were established and East German crossing regulations were slightly relaxed, although the fortifications were as rigorously maintained as ever.
Therefore, complex cross-regulations were observed between different M. tuberculosis RelBE-like modules.
The net result of this cross-regulation is survival.
The opposite question related to the presumed cross-regulation is whether type I IFN suppresses TNFα production.
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