Distance in the ML method is calculated with the Haldane mapping function, which assumes no cross-over interference and may overestimate distances when interference is present.
Double recombination is unlikely to occur between markers <10 cM apart on a single chromosome in a mapping population of a few hundred chromosomes, due to cross-over interference during meiosis.
Joinmap calculates genetic distances using Haldane's mapping function which assumes no cross-over interference and therefore results in larger genetic maps than those generated using the Kosambi mapping function (Salomé et al. 2011).
Since cross-over interference is common in the honeybee and other higher organisms [e.g. [ 23, 53, 54]] it seems prudent to consider this mechanism for establishing the bumblebee map.
Power lines cross over it.
Only Jean tried to cross over".
"It could definitely cross over".
Is Indian art about to cross over?
"Tell her to cross over".
"For that reason, the Iraqi people want to ensure that these reactions stay in a positive frame and do not cross over into interference that damages the results of the democratic process".
Reviewer #2: Suggestion: Title: Adjacent homozygous and heterozygous regions reciprocally enhance and suppress crossing-over in an interference-mediated process.
