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In addition, the antibody against N-terminus of Aβ can cross bind to APP on the surface of neurons and promote the generation of Aβ [ 5, 20], and binding of autoantibodies to neurons is associated with increased level of intracellular Aβ [ 29]; suggesting that antibodies against Aβ or neuronal surface APP molecule may also increase Aβ production once they enter the brain.
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One minute after Italy had taken the lead their captain dived full length at his near post to head clear a cross bound for Oliver Neuville's feet and a certain equaliser.
And if David Jarolim had not stretched out to intercept a Zoltan Gera cross bound for Zamora's replacement Clint Dempsey on the hour, the Cottagers would have been in dreamland.
Bound antibodies were then cross bound to the polymer reagent Envision+ anti-rabbit-HRP® (Dako, Glostrup, Denmark) for 30 minutes at room temperature.
IGFs and insulin are proficient to cross-bind to each other's receptor, although with much weaker binding affinity than that for the preferred ligand [ 33, 34].
The main factor limiting their long-term administration is the fact that they cross-bind to other oxo-steroid receptors.
Our south-north crossing bound our family with the emotional ties of shared adversity, and it's Sullivan's contention that road trips bind us together as a nation.
There have been seven church burnings over the past six months, and the most recent, a week ago in a town in Upper Egypt, sent Copts back to Maspiro waving crosses bound with rags to demand an investigation and greater protection.
Every one of my cooks was festooned with prison tats: screaming skulls, Jesus on hypodermic crosses, bound in barbed wire, gang tats, flaming dice, swastikas, SS flashes, Born to Lose, Born Dead, Love Hate, Mom, portraits of the Madonna, wives, girlfriends, Ozzy Osbourne.
E2 has a high affinity for ER-β and triggers a suppressive effect in JKT-1 cells, whereas E2 coupled to BSA, which prevents membrane crossing, binds to an ncmER and promotes cell proliferation by activating rapid cell signaling, including PKA and MAPK pathways (Bouskine et al. 2008).
Her parents first met on a train departing from King's Cross Station bound for Arbroath in 1964.
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