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At present we can only conclude that appropriate oxygenation is essential in any critically traumatized patient.
However, if adequate skills are not available, then critically traumatized patients may rather benefit from adequate ventilation using less invasive means (e.g. bag valve mask ventilation if transport times are short) [ 25, 26].
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We aimed to determine the prevalence of ARC in a cohort of septic and traumatized critically ill patients, while also examining demographic, physiological and illness severity characteristics that may help identify this phenomenon.
The aims of this pilot prospective observational study were, therefore, to: a) describe the prevalence of ARC in a cohort of septic and traumatized critically ill patients receiving antibacterial therapy; b) correlate CLCR and CI in these patients; and c) examine demographic, physiological and illness severity characteristics that may help to identify patients manifesting ARC.
In cases of critically ill or severely traumatized patients the widely used monitoring techniques like pulse oximetry and capnometry are limited and not acceptable alternatives to blood gas analysis.
Consecutive traumatized and septic critically ill patients, receiving antibacterial therapy, with a plasma creatinine concentration ≤110 μmol/L, were eligible for enrolment.
This pilot investigation, in the context of a larger study examining β-lactam antibacterial PK in the critically ill [ 29], has explored the relationship between CI and CLCR in a cohort of septic and traumatized patients with normal plasma creatinine concentrations.
"I was completely traumatized.
She is traumatized.
Our children are traumatized.
It's traumatized everybody".
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