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To critically monitor ryanodine receptors' (RyR2) Ca2+ nano-domains, we combined the use of genetically engineered RyR2-targeted pericam probes, (FKBP-YCaMP, Kd = 150 nM, or FKBP-GCaMP6, Kd = 240 nM) with rapid total internal reflectance fluorescence (TIRF) microscopy (resolution, ∼80 nm).
Modulation of intracellular levels of iron (via chelation with deferoxamine (DFO)) also disrupts cell survival, implicating a need to critically monitor and maintain appropriate levels of cellular iron for cell survival.
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Moreover, online monitoring series from critically ill patients during multiparameter monitoring were also compared.
The letter, obtained by FairTest, an organization that critically monitors the use of standardized tests in college admissions, lifts a corner on an aspect of higher education admissions that is usually cloaked in euphemism and ambiguity.
The aerospace industry has high quality requirements for fabrication, and critically monitors manufacturing processes as well as inspecting components and assemblies.
In a similar manner, a small-scale reinforced concrete structure was erected in an open and critically monitored for defects caused by environmental factors of degradations.
Evidence gathered till date projects CHIP as a highly regulated protein whose function in the cell is critically monitored.
The formation of secondary structure and primer dimmers were critically monitored to get success of the primers.
Furthermore, it should be critically monitored whether Phase 0 trials contribute to faster drug development without putting patients at unacceptable risks.
This fact may be due to preselection of patients in clinical trials; therefore, the incidence of cardiotoxic effects in unselected patient populations needs to be critically monitored.
Even though judgment based on values tends to be present in this type of assessment, the relevance of consolidating an assessment culture which critically monitors educational practices was also observed.
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CEO of Professional Science Editing for Scientists @ prosciediting.com