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However, future studies will need to identify which of the RNAs generated from the Snord116 locus are critically lost in PWS, and if loss of multiple RNAs underlies the complex phenotype of PWS.
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"We urgently need to build a new police force of local patriots, but we are critically losing time".
A fraction of damaged cells will critically lose their ability to live, but a different subset of cells may be more difficult to identify and eliminate: viable but suboptimal cells that, if unnoticed, may adversely affect the whole organism (Moskalev et al., 2013).
Directed by Ernst Lubitsch – the sophisticated director of comedies of manners like Trouble in Paradise – it depicts the life of the Russian Tsar Paul I. Only small fragments of the film remain, and it is one of the most critically praised lost movies ever.
These wage increases are critically important; lost in the headlines about huge CEO salaries is the fact that on average, more than 30% of the 1.7 million people who work in retail banks make less than $15 per hour.
The New Zealand Warriors sat as high as fourth on the premiership ladder just two rounds back but seem destined to miss the eight after a horror Saturday clash with Manly that saw the Sea Eagles win 32-12 at Mt Smart and more critically, New Zealand lose star halfback Shaun Johnson.
The critically ill lose their capability to understand and to make a judgement, and they therefore constitute a 'vulnerable population' needing special and reinforced protection [ 2].
World of Warcraft, based on Activision's online role playing game, was critically panned and lost a reported $15m on a budget of $160m.
Obese critically ill mice lost relatively more adipose tissue mass than lean mice but ultimately retained more adipose tissue [6].
These animals are critically endangered, having lost half of their population in one generation.
Fasted critically ill rabbits lost weight, which was attenuated by increasing intravenous glucose load.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com