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"critically involved" is correct and usable in written English.
It can be used to refer to a person or thing which is deeply engaged in a project or activity and is essential to its success. For example, "He was critically involved in the planning of the project, making sure that all necessary steps were taken."
Exact(59)
Therefore, TDP-43 is critically involved in miRNA biogenesis.
Müller glial cells are critically involved in retinal inflammatory processes.
Prefrontal and temporal regions are critically involved in these functions.
There is strong evidence that nitric oxide is critically involved in migraine pathophysiology.
However, there is strong evidence that nitric oxide (NO) is critically involved in migraine pathophysiology [4].
In addition, ROR1 is critically involved in progression of a number of blood and solid malignancies.
Specifically, ILC2-derived IL-5 is critically involved in increased IgM production (Drake et al., 2016).
Here, the epithelial-mesenchymal crosstalk is known to be critically involved in the gradual process.
Wnt signaling is critically involved in the differentiation of human Mesenchymal Stem Cells (hMSC).
Studies from site-directed mutants revealed that Asp170 is critically involved in substrate hydroxylation.
The left inferior frontal gyrus (IFG) is critically involved in the neuronal network subserving ER.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com