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Scientists do not know how much of the slow-growing red and pink coral now exists in underwater stocks; but they point to declines in known fishing zones as evidence that it has been critically depleted.
Conventional agriculture with intensive tillage and high inputs of synthetic chemicals has critically depleted the soil C pools.
His goal: a no fishing zone which will "let the ocean heal" after decades of commercial fishing and poaching that has critically depleted the oceans.
If a bird decides not to return on a particular night due to predation risk, the on-duty bird may decide to leave the nest if its body reserves are critically depleted.
In strongly declining and threatened populations with critically depleted genetic diversity, both reduced adaptive potential and the possible fixation of deleterious alleles by genetic drift due to small effective population sizes can affect the long term survival capacity of populations and species [ 45].
It is noteworthy that the populations of both the entire Bay of Fundy and the Atlantic coast of Nova Scotia are critically depleted, the populations of the Inner Bay of Fundy having been listed as endangered under Canada's Species At Risk Act (COSEWIC 2006; NASCO 2007).
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The vaquita, a porpoise living in waters where the Colorado River empties into the Gulf of California, is critically endangered, biologists say, depleted by fishing nets and the disruptions in the river's flow from dam construction.
Practically, GR-mediated delivery of amiR-Hsp90 plasmid in tumor-bearing mice, depleted Hsp90, critically down-regulated levels of Akt, VEGFR2 and other Hsp90-client proteins but up-regulated wild-type p53 in tumor.
Occurrence of CN is however consistently higher in diabetics, congestive heart failure patients, volume depleted patients, critically ill patients and especially in patients suffering from chronic kidney disease (CKD) [ 7, 10- 12].
Available data make it highly unlikely that all critically ill patients are depleted in glutamine, as only approximately one third of patients admitted to the ICU have a plasma glutamine concentration < 420 μmol/l.
Given that critically ill patients are prone to inflammation, cardiovascular instability, and depleted antioxidant mechanisms, the most rational practice may be to supply oxygen conservatively and titrate the therapy carefully to the patient's needs.
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