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Of particular importance, our data revealed that the GAERS mutation critically alters the interaction of calnexin with Cav3.2, resulting in a significant increase in surface expression of the channel, which may account for the elevated T-type Ca2+ conductance in GAERS reticular thalamic neurons.
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The loss of his daughter critically altered his once-tentative grasp on his own accountability.
Deformation during microwave drying was found to critically alter material structure that significantly affected microwave absorption, heat and moisture transport within the material.
However, a 2007 Centers for Medicare and Medicaid Services regulatory policy, Conditions of Participation (COP), which mandates publically reported transplant center performance assessment and outcomes-based auditing, critically altered waitlist management and clinical decision making.
Oral administration of malathion to mice infected with 20, 40 or 60 S. mansoni cercariae adversely affect architecture of liver and spleen and critically alter hematological, biochemical, histological and hepatic enzymes parameters significantly more than the controls.
They show that the flow in the runner, and thus the resulting torque applied to the shaft, is critically altered by a cyclic growth, shedding and complete collapse of cavitation on the suction side of the runner blades.
In the early years of her graduate studies at Harvard, Weaver bucked against the common thinking that punishment was not a core concern for political science, successfully arguing that incarceration and surveillance influenced America's post-war institutions in ways that critically altered the racial politics and inequality of later decades.
Said waste has critically altered the local ecosystem.
And as a result of the shooting, Rudolph argues, Giffords' pivotal voice "has been sidelined at a time when moderate voices are desperately needed". Unfortunately, Giffords wasn't the only shooting victim whose voice could have critically altered immigration politics in Arizona.
As such, the integrity of chaperone systems can critically alter the progression of diseases associated with ageing, DNA damage and chronic injury [1], [2].
A critically altered region in Xist might also be outside of the area we have analyzed, even though this area includes all the regions that have been shown to be important for silencing and localization [68], [77].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com