Dermatological toxicities, especially rhagades induced by EGFR inhibitors, critically affect patients' health-related quality of life and, as a consequence, the dose intensity of EGFR inhibitors and, thus, the effectiveness of antineoplastic regimens.
Importantly, excitability changes were abnormal in the most clinically affected patients, critically indicating that the excitability changes relate to the process of neurodegeneration and compensatory partial regeneration.
Chronic renal disease is a serious, lifelong condition that critically affects the lives of renal patients, and concern about this is likely to be important in explaining why patients want to use the system.
Interestingly, one of the mutations among patients (N248D) is critically affecting one of the antibody binding sites.
6 Factors such as whether the technique is too complex or too onerous to learn, and the strength of physician or patient preferences might critically affect its adoption.
In primary health care, provider-patient interaction is fundamental platform and critically affects service delivery.
Introduction Medication errors are common in critically ill patients, [1] and have the potential to adversely affect patient safety [2].
Pain in the critically unwell can lead to significant physiological and psychological consequences, and may affect patient outcome.
Its derangement, defined as "microcirculatory shock" [2], is recognised as an important cause of organ dysfunction in critically ill patients, affected by various disease states, such as sepsis, severe trauma, haemorrhagic shock and post-cardiac arrest [2 5].
Only critically ill patients affected by pandemic H1N1 virus infection in stage AKI III are independently associated with increased mortality.
