Sentence examples for critical virus from inspiring English sources

When the dosage was further reduced (2.5 × 10 pfu/animal), virus and mock treated animals showed no significant differences (Supporting Information Fig S7E and Table S2), indicating that a critical virus dose is required in order to achieve a therapeutic effect.

To further investigate whether only domains I-II of GBV-B contain critical, virus-specific RNA replication elements, we similarly analyzed the chimeric replicons in which translation was uncoupled from replication and no longer dependent on the GBV-B 5'NTR.

We show that domains I and II of the GBV-B 5'NTR contain essential and virus-specific RNA replication signals, whereas domain III, which is essential for virus translation, does not play a critical, virus-specific role in RNA replication.

Therefore, the current study identified critical virus-cell interactions that are likely to improve the development of BEVS in future studies.

To examine if the S183 and T185 residues are critical for virus viability, we generated viruses possessing mutant M1 using plasmid-based reverse genetic system for A/WSN/1933 (WSN).

The protease role of nsP2 is critical for virus replication as only the virus protease activity is used for processing of the viral non-structural polypeptide.

The protease role of nsP2 is critical for virus replication as only the virus protease activity is used for processing the viral non-structural polypeptide.

The protease role of alphavirus nsP2 is critical for virus replication as only the virus protease processes the viral non-structural polypeptide.

One of the viral proteins, NS3/4A, has serine protease activity that is critical for virus maturation.

The identification of proteins critical for virus replication may lead to the development of novel, cell-based inhibitors.

In this study, we determined that molecular determinants of DENV2 envelope protein critical for virus entry during non-ADE infection are also required for ADE infection mediated by FcγRIIA, and binding of virus-Ab complexes with FcγRIIA alone is not sufficient for ADE of infection.