Sentence examples for critical trigger from inspiring English sources

Given the known association of cancer with some viruses, a critical trigger might be a viral incursion that might be context dependent.

IAVs first interact with the host through epithelial cells, and the viral RNA containing a 5′-triphosphate group is thought to be the critical trigger for activation of effective innate immunity via pattern recognition receptors-dependent signaling pathways.

"Mutaz and Basma were keen to help by providing food to these refugee families, since not having food is a critical trigger for many families in the Collateral Repair Project community to take risky decisions, like pulling children out of school to beg on the streets or even returning back to their war torn countries," Habersky wrote.

Thus, rafts behave as recruitment platforms to facilitate and potentiate downstream signaling events, with Fas functioning as a critical trigger of the apoptotic process.

Taken together, the results presented in this study provide initial safety and immunogenicity data for a vaccine mimicking what we believe is a critical trigger for naturally occurring effective tumor immune responses seen in PND patients.

Based on such observations it is suggested that the decline of CD4 Tcm subset may be the critical trigger that serves as the initiating event for the immune deficiency in general towards onset of AIDS in the macaque model, and by extrapolation to HIV infected humans [23].

In conclusion, our findings suggest that infection of mononuclear phagocytes is critical, triggering a cascade of events involving cytokines/chemokines and oxygen free radicals.

Further, the energy absorption efficiency is proposed to optimize the specific energy absorption density and critical triggering force of activating energy absorption, and is correlated with deformation mechanism and geometric parameters of FSS structures.

Further collapse of the contact would further decrease the internalization and bring the receptor density above critical, triggering contact expansion.

In all cases, increased variability in expression levels would facilitate reaching of the critical "triggering" parameters, thus its direct measurement may have diagnostic and prognostic value.

Environmental factors such as diet are critical triggers for the development of type 1 diabetes [ 5].