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Since phase III definitive efficacy trials with cancer endpoints require a lengthy timeframe and considerable resources for completion, it is critical to first optimize agent delivery and trial design and to determine preliminary efficacy via the conduct of phase II trials.
I think it's critical to first frame and understand this discussion with the broader political economy of Internet software platforms.
This observation is important, because others have suggested that it is critical to first develop a professional identity before developing interprofessional competencies (Khalili et al. 2013).
To effectively design and implement a data infrastructure, which aims to mobilize and cross-fertilize the institutional talents and expertise and to facilitate knowledge sharing for collaborative action, it is critical to first chart the practical steps needed for a balanced and integrated development.
For instance, it was critical to first establish whether the anterior nares are inhabited either by a defined, characteristic microbiota or by transient microbial assemblages that result from perpetually changing exposures to bioaerosols, dust particles, water, etc.
Accordingly, controlling macrophage plasticity is critical to first battle pathogens and then resolve the resulting inflammation to prevent tissue damage.
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Growing Lime's traction is critical to Fifth Wall, which led the startup's $70 million Series B extension in February, and joined its $335 million Series C in July.
There will be demos, tutorials, and presentations on how to be safe". Growing Lime's traction is critical to Fifth Wall, which led the startup's $70 million Series B extension in February, and joined its $335 million Series C in July.
Sustained suppression of viral replication is also critical to second phase recovery [ 20, 21] and we confirmed that viral load at 16 weeks was a strong independent predictor of subsequent immunological recovery.
Critical to the first steps of photosynthesis are proteins called light-harvesting complexes, or LHCs.
It should also offer an indication of the extent to which Mrs. Clinton feels obligated to the groups that were critical to her first campaign for public office.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com