Sentence examples for critical target tissue from inspiring English sources

The hematopoietic system is the most critical target tissue following inhalation exposure to benzene in either humans or animals.

Finally, circulating serum lipid concentration is likely to be a good surrogate for critical target tissue exposure concentrations in a range of organs and tissues because of the lipophilic nature of dioxin-like compounds.

Either treatment would reach the critical target tissues and trigger fat accretion, but exposure to 4‑HNE in the medium would generate more total 4‑HNE adducts.

Breast cancer metastasis is a multi-step process that starts with evasion of cancer cells from the primary tumor, migration through the blood stream and lymphatic ducts, and homing into critical target tissues, creating a life-threatening disease [ 1].

Once diagnosis and staging of prostate cancer have been completed (and BT is selected as a treatment option), the identification of critical target and normal tissue structures is made.

The choice of a water-soluble prodrug such as ZD6126, which is stably entrapped into the aqueous interior, may be critical for successful target tissue delivery.

The vascular endothelium is a critical target compartment involved in tissue response to radiation exposure and strongly participates in the initiation and development of radiation lesions [ 5, 14].

Closed-loop temperature and impedance control prevent thermal injury and facilitate longer treatment times at critical target temperatures, allowing all soft tissue in the treatment zone to reach a uniform temperature distribution.

The association between higher expression of αv integrin, a critical target of intetumumab, in tumour tissue and SD as opposed to PD is intriguing, although similar correlations were not observed with clinical response, PFS, or OS.

Genetic and pharmacological manipulation of both complement levels and complement activation in mouse models of TBI are reported to be highly neuroprotective, suggesting the complement cascade is a critical target for managing post-TBI tissue damage.

IPMK-mediated AMPK signaling also provides another potential regulatory layer critical for allowing target tissues and the whole body to accurately gauge and adapt energy and nutrient levels.