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Rac1 is a critical regulator of cell cytoskeletal organization and transcriptional regulation.
BMAL1 is a critical regulator of the circadian clock.
We propose that basonuclin is a critical regulator for corneal epithelium homeostasis.
Mammalian target of rapamycin (mTOR)/S6K1 signalling emerges as a critical regulator of aging.
Collectively, these results also implicate c-Src as a critical regulator of VEGF in hypoxia.
Akt has previously been established as a critical regulator of cell cycle progression (reviewed in [9]).
These studies indicated that VHL is a critical regulator of the ubiquitous oxygen-sensing pathway.
The granulocyte colony-stimulating factor receptor (G-CSFR) is a critical regulator of granulopoiesis.
Most recently, IGF-II has also been described as a critical regulator of hESC self-renewal.
(iii) Activation of CaMKII is a novel and critical regulator of cytoskeleton in prostate cancer.
These studies establish Lrp4 as a critical regulator of ureteric budding in both mice and humans.
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