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Because some critical prognostic variables such as disease status and lymphoma subtype violated the proportional hazard assumption in 3 donor groups, we controlled for them by stratified analysis to answer the donor source risk association; thus the analysis was not designed to address influence of disease and patient-related factors on outcomes.
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This factor further highlights the critical importance of conducting large randomised trials as they ensure a balance of both known and unknown prognostic variables through the randomisation process.
Another critical issue for is properly acknowledging the heterogeneity of patient populations, treatment of the patients, and the available 'standard' prognostic variables used to adjust the effect of the factor of interest in each study.
In our series, mitotic count was one of the most important prognostic variables.
Survival with inoperable lung cancer: an integration of prognostic variables based on simple clinical criteria.
Anemia and red blood cell (RBC) transfusion dependence are independent adverse prognostic variables for survival1,2,3.
For improving predicative accuracy of prognostic systems, new prognostic algorithms have been designed combining independent prognostic variables.
Tumor grade/stage and complete surgical resection for high-grade tumors are important prognostic variables.
Yang Q, Mori I, Sakurai T, et al. Correlation between nuclear grade and biological prognostic variables in invasive breast cancer.
Furthermore, investigators should report baseline comparisons on important prognostic variables.
The identification of intralymphatic as distinct from blood vascular localization may provide critical prognostic and therapeutic information.
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CEO of Professional Science Editing for Scientists @ prosciediting.com