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This gap occasionally causes a critical positioning error between the other leg and its desired station.
Investigation of a critical positioning scenario where only two ANs are available.
The chemical reactivity of ribocations is extremely high, requiring critical positioning of C1′ and the water molecule to prevent reaction of the ribocation with nearby protein nucleophiles.
The combination of critical positioning, reduced ROM and metal on metal is not ideal, but metal on metal is the only choice for HRA.
A crucial aspect of oestrogen-ER interaction is the complete envelopment of the steroid in a hydrophobic pocket within the ligand binding domain due to the critical positioning of a 'lid' formed by helix 12 of the ER.
Actin three-dimensional molecular modeling revealed critical positioning of R179 at the interface between the two strands of filamentous actin and destabilization of inter-strand bundling by the R179H mutation, explaining the severe associated phenotype.
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"That's a critical position," Carter said.
The critical position arose after 56 Nf8.
Woolcott said coalitions such as Brics (China, India, Brazil, South Africa and Russia) "occupy critical positions".
The deal underscored the critical position "Friends" holds on NBC's prime-time schedule.
"With that little shopping spree, those critical positions will hold us well," Groh said.
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