Critical overlap length was computed for three natural composites-nacre, spider-silk and, collagen in bone/tendon, and showed reasonable agreement with experimental data.
Thus, this GDAP1 region contains critical overlapping motifs defining intracellular targeting by the TA concomitant with functional aspects.
Similar to p120-catenin, β-catenin protects the cadherin cytoplasmic domain from degradation by blocking sites that overlap with critical binding sites (Huber et al., 2001).
The duties of critical care outreach teams overlap with that of MET and may be additive to any outcome benefit associated with MET.
A candidate with wide geographic appeal who can best exploit Trump's vulnerabilities (age, cluelessness, meanness, incompetence) may have a greater chance than candidates who are at a disadvantage in critical states and whose deficits overlap with Trump's.
These time windows overlap with the critical period for response inhibition in visual antisaccade tasks [ 29, 30, 47].
Interestingly, the SOR region of our five 4q terminal deletion cases does not overlap with this cardiovascular critical region, suggesting that our 4.6 Mb region represents a novel CHD critical locus.
