Increased expression of HO-1 and elevated COHb levels have been demonstrated in patients with critical disease, chronic obstructive pulmonary disease (COPD), systemic inflammatory response syndrome and acute respiratory distress syndrome [ 12- 14].
APACHE: Acute Physiology and Chronic Health Evaluation; CHF: chronic heart failure; CIPNM: critical illness polyneuromyopathy; COPD: Chronic Obstructive Pulmonary Disease; EMS: electrical muscle stimulation; IL-6: interleukin-6; MRC Medical Research Councill; OR: odds ratio; SAPS: Simplified Acute Physiology; SD: standard deviation; SOFA: Sequential Organ Failure Assessment.
To evaluate the therapeutic value of endovascular techniques for the treatment of profunda femoris artery obstructive disease (PFAOD) in critical limb ischaemia (CLI) patients, with technically demanding open profunda repair.
Thrombin is a serine protease and regulator of hemostasis that plays a critical role in the formation of obstructive blood clots, or thrombosis, that is a life-threatening condition associated with numerous diseases such as atherosclerosis and stroke.
A total of 23 patients were recruited from a large group of 63 patients with chronic obstructive pulmonary disease admitted to critical care department.
The main evidence-based clinical indications for NIV use in the critical care setting are exacerbations of chronic obstructive pulmonary disease [ 3, 4] and acute cardiogenic pulmonary edema [ 5– 8].
The most frequent underlying diagnoses for the need of critical care for the study population included pneumonia (21%), obstructive lung diseases (asthma and chronic obstructive pulmonary disease) (14%), postoperative non-vascular surgery (14%), and trauma and burn (13%).
The purpose of this review was to detail part of these clinical uses, focusing mainly on obstructive respiratory diseases in the adult critical care setting, and therefore excluding pediatric studies and also studies solely centered on helium-driven nebulization.
External ventricular drains (EVD) are commonly used in critical care units for the treatment of acute obstructive hydrocephalus (subarachnoid hemorrhage, intracranial hemorrhage or brain tumors), for intracranial pressure monitoring or for the administration of intrathecal medication.
However critical congenital heart defects such as left-sided obstructive lesions were rare, suggesting the poor survival of affected children, and the likelihood that the data available underestimate the true prevalence of CHD.
