Sentence examples for critical mutations from inspiring English sources

Neither mutational nor distance measurements appear to identify kinetically critical mutations quantitatively, or to separate N-glycan and sialic acid interactions.

The challenge is in identifying the critical mutations in a genome.

The more critical mutations that are added to the database, the more powerful the database becomes.

2005 A gene hunt reveals critical mutations that increase the risk of macular degeneration, a common cause of blindness.

In total, 13 critical mutations demonstrated ligand-specific effects (≥2.5-fold difference in activity for at least one pair-wise ligand comparison) (Fig. 3b; Supplementary Table S3).

We suspect that a few of the missense mutations are the probable cause of its Forssman negativity although there may be additional and more critical mutations in the unsequenced region of the gene.

Another critical mutation is H87Y, which introduced a perfect parallel π π stacking with BV.

The different WP2 strains all carry the same AT base pair at the critical mutation site within the trpE gene.

Using this definition, we suggest two approximate formulas to estimate the critical mutation rate after which the quasispecies delocalization occurs.

Furthermore, it is shown that space, which involves a lower critical mutation rate, broadens the conditions at which the survival-of-the-flattest may occur.

The last estimate stresses the fact that the inverse dependence of the critical mutation rate on the sequence length is not a generally valid fact.