Sentence examples for critical malaria from inspiring English sources

Another interesting feature of our study is that two relatively different pharmacophores appear to be acting against the same critical malaria target.

In this study, we used bioinformatics, existing knowledge of mammalian signaling pathways, and signaling assays in An. gambiae cells to provide a more comprehensive understanding of the likely roles of the MAPK cascades in innate immunity of An. gambiae, a critical malaria vector mosquito for which an annotated genome sequence is available [ 33].

From the criteria described in the medical literature to define critical malaria, the patient fulfilled the following: acute renal failure, acute respiratory distress syndrome, metabolic acidosis, altered level of consciousness, macroscopic hemoglobinuria, hyperparasitism and hyperbilirubinemia, related to a lethality rate of over 10% depending on early treatment and available resources.

Identifying the location and size of residual foci of infections is critical where malaria elimination is the primary goal.

A careful balance of pro- and anti-inflammatory cytokine levels appears to be critical to malaria outcome [23].

Sporozoite invasion of the anopheline salivary gland is critical for malaria parasite transmission and yet it is one of the most poorly studied stages of this deadly pathogen.

Robust and responsive surveillance systems are critical for malaria elimination.

The widespread availability of 8-aminoquinoline, such as primaquine and in the future, tafenoquine, is critical in malaria elimination efforts in areas where Plasmodium vivax is prevalent.

Invasion of the mosquito salivary glands by Plasmodium is a critical step for malaria transmission.

All models predict that human population density is the critical factor determining malaria risk.

The wide variety of immune responses found in different adjuvant formulations stresses the importance of adjuvants as a critical component in malaria vaccine development.