The post-translational modifications to cysteine on Trx-1 appear critical to its localisation and function in a range of cells.
We use a geometric method of spatial analysis (SpaDiS™), which requires neither statistics nor algebraic models to show that crustal architecture is critical in the localisation of kimberlites.
Some of these proteins have the pentapeptide repeats, which are known to be critical for the localisation of glycolipids [ 108].
It has been reported that the binding of MYO10 to PtdIns 3,4,5 P3 is critical for the localisation of MYO10 and filopodium formation (Plantard et al, 2010).
ASPP2 is critical for the localisation of Par3 at the level of tight junctions in epithelial cells and, therefore, has a crucial role in the establishment and maintenance of apical basal polarity in epithelial cells in culture.
This nuclear localisation is critical in mediating the invasion of PSCs and, consequently, cancer cells.
Evidence from analysis of DRMs (Kupzig et al., 2003) and super-resolution imaging (Lehmann et al., 2011) suggests that the presence of the GPI anchor is critical for membrane microdomain localisation of CD317.
Chromatin remodeling associated to DNA synthesis, CTs relative positioning, loci spatial proximity, intermingling of chromatin loops and transcriptional activity could be critical to determine chromosome damage localisation, genomic instability and cancer-prone translocation frequencies.
No further radiation to the prostate is usually possible and hence the critical need for accurate prostate localisation and seed placement from the outset.
E-cadherin also however acts as a negative regulator of the WNT signalling cascade by controlling the cellular localisation of the critical mediator β-catenin.
