Sentence examples for critical interacting from inspiring English sources
The docking analyses revealed that Ala-22, Glu-23, Ser-65, Gln-67, Tyr-141, Leu-142, Asp-143, Phe-144 and Ala-145 were critical interacting residues for receptor-ligand interactions.
The results also demonstrated Y116 on the outer alpha helix loop of LLR3 as a critical interacting partner since mutation of this residue to serine abrogated ectodomain-ectodomain interactions.
Capicua, a critical interacting molecule to hAtx1 that mediates physiological functions of hAtx1 through binding to phosphorylated Ser776 proximal to the AXH domain [16], [17], is also highly conserved between human and Drosophila.
The forkhead protein FOXA1 is a critical interacting partner of the AR, functioning as a pioneer factor to modulate chromatin accessibility and facilitate transcription (Jozwik & Carroll, 2012).
As might be expected from the high level of conservation in the critical interacting amino acids in the receptor-binding domain of the camel and human MERS-CoV isolates (online Technical Appendix Table), we show that camel MERS-CoV can infect human Huh-7 cells by using the same entry receptor as the human MERS-CoV isolates (15 ).
They propagate by recruiting host-encoded PrPC although the critical interacting proteins and the reasons for the differences in susceptibility of distinct cell lines and populations are unknown.
On the other side, the positive charge of lysine residues were considered to be critical for interacting with the anionic interface as a result of initial electrostatic interaction (Koba et al. 2009).
The critical primase interacting residues from helicase are partially conserved.
Because both CHIP and LRRK2 have multiple domains (see Supplemental Figure S1), we sought to further delineate which domains of CHIP are critical for interacting with different regions of LRRK2.
All CDCs characterized to date contain a C-terminal Ig domain that is critical for interacting with lipid or protein cofactors.
The negatively charged Glu1112, critical for interacting with a positively charged surface formed by ANK repeats R2 and R3, is highlighted with a red box.
