Sentence examples for critical inflammation from inspiring English sources

Quantitative RT-PCR studies conducted on 23 critical inflammation and immune response markers showed major alterations in gene expression profile by FLG, FLG-COOH and FLG-PEG treated animals.

In addition to the metalloproteinase-mediated generation of critical inflammation triggers, metalloproteinases are, in turn, utilized by immune cells to further propagate the inflammatory reaction.

Nevertheless, the significance of these critical inflammation proteins to the risk of CALs or intravenous immunoglobulin (IVIG -resistance IVIG -resistancergely unknown.

Prior work suggests that COX-2, a critical inflammation inducer in peripheral tissues, is also involved in AD progression via inducing the activation of astrocytes or microglia cells (Akiyama et al., 2000).

These researchers are a healthy mix of basic scientists and clinician scientists whose research activities have led them to embrace experimental research in distinct areas of critical care (inflammation, immunity, respiratory, metabolic, neurological, endocrine, trauma, and so forth).

However, when injury exceeds a critical threshold, inflammation is usually clinically evident and constructive repair is involved.

The key role of PAR4 suggested to us that platelet activation may be critical for inflammation to develop following sTF injection, as PAR-4 is the main platelet protease receptor in mice.

Therefore, we compared quantitatively the expression of different genes which are critical for inflammation (TNFa and IL-1b) in the eyes of KTA048 mutants and wild-types at E12.5, E15.5 and P10 by qRT-PCR.

Tumor necrosis factor (TNF) is a pleiotropic cytokine critical for inflammation during innate and adaptive immune responses, orchestrating cytokine expression via activation of the canonical NF- κB (nuclear factor kappa-light-chain-enhancer of activated B cells) signaling cascade.

NIK has also been shown to be critical for inflammation-induced osteoclastogenesis, as NIK-deficient mice were largely resistant to arthritis with less osteoclastogenesis and less bone erosion [ 31].

Correct assembly and regulation of inflammasomes is critical for mediating inflammation and preventing uncontrolled inflammation under infectious and sterile conditions.