Exact(6)
Although it has been assumed that ERK1 and 2 were functionally equivalent, recent studies have shown critical functional differences between these two proteins.
ERK1 and ERK2 have been assumed to be functionally equivalent; recent studies have distinguished critical functional differences between these two proteins.
The first approximation to classifying critical functional differences has been to group species into functional groups, which is often based on broad morphological and physiological similarities (e.g., C4, C3, legumes, etc).
We assume that since PD is such a good explanatory variable, it provides a measure of diversity that must be associated with critical functional differences among species within a community that contribute to maximization of productivity.
The results of these experiments clearly point toward critical functional differences in atypical and classical MBCs.
Such critical functional differences mean it is important to develop a cognate SSB probe that is compatible with the biological system under study.
Similar(54)
To test whether this was critical for the functional differences observed, site-directed substitution of Valine-202 to Threonine was employed to generate the H1.2 variant H1.2V202T-EGFP.
These residues are potentially the most critical in defining the structural basis for functional differences between hMC4R and hMC1R.
Conversely, functional differences – even in only a few critical pathways – could reflect subtle, but important habitat differences and dramatically altered ecosystem services.
The structure of PvH2B showed that it has certain differences from that of its host at critical functional sites (viz acetylation, methylation, trypsin cleavage, DNA-binding and inter-histone interaction) which are required for general gene expression and DNA packaging.
These results and the findings of our study suggest that PIN3 and PEX4 polymorphisms present specific functional differences in p53 protein variants, having an impact on events that are critical for embryo implantation and/or early development.
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