Sentence examples for critical for the proper function from inspiring English sources

The formation of islets with the stereotypical architecture of a β cell core surrounded by α, δ, ε and PP cells is thought to be critical for the proper function of pancreatic islets [17], [18], [19], [20], [21].

Together with the fact that osu1-2 (not0Y) does not reduce its transcript level (Figure 6C), this indicates that N560 is critical for the proper function of the OSU1-encoded protein.

DOI: http://dx.doi.org/10.7554/eLife.03941.001 Dystroglycan is a protein that is critical for the proper function of many tissues, especially muscles and brain.

This form of gene regulation plays an important role in developmental systems and is critical for the proper function of numerous biological pathways.

Furthermore, an exogenous pre-miRNA hairpin is more effective at promoting the silencing of targets than a duplex RNA, suggesting that the coupling of Dicer processing and RISC loading is critical for the proper function of miRNAs [ 45].

The apparent design feature, which requires complex molecular control of hydration on the cytoplasmic side (e.g., the large-scale changes are insufficient), suggests moreover that this functional property has been honed carefully by natural selection and that it is critical for the proper function of the pump.

These patterns can be critical for the proper functioning of a microbial community.

Patterning, reflecting the relative spatial positioning of individuals with respect to each other, can be critical for the proper functioning of a community.

AS, which has a well-established role in cell differentiation [ 57, 58], may be critical for the proper functioning of the placenta, an organ composed of a variety of differentiated cell types, each with its own specific functions during pregnancy.

It is clear that the distinct system responses are critical for the proper functioning of the DARPP-32 signaling network, and that a better elucidation of their mechanistic implementation and robustness could possibly help deepen our understanding of its functioning, identify weak points in the system that are associated with disease outcomes, and provide targets for therapeutic interventions.

Although sensory neurons constitute a critical component for the proper function of the nervous system, the in vitro differentiation of functional sensory neurons from human stem cells has not yet been reported.