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JNR Sky's homegrown drama is tempting TV critical fate with that title, and so it has proven.
By Mark O'Connell February 17 , 2012William Gaddis, in the closing pages of his colossal 1955 novel "The Recognitions," inserts a brief scene that manages to be at once rancorously funny, brazenly self-referential, and spookily prescient about the critical fate that lay in store for his work.
William Gaddis, in the closing pages of his colossal 1955 novel "The Recognitions," inserts a brief scene that manages to be at once rancorously funny, brazenly self-referential, and spookily prescient about the critical fate that lay in store for his work.
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The concentration of the morphogen is critical for fate decisions in the responding cells.
Sporulation is a critical cell fate that allows B. subtilis to adopt a resistant structure, thereby allowing its survival in extreme, unfavorable conditions.
This epigenetic mechanism is important for priming gene regulatory networks for critical cell fate decisions in rapidly proliferating postimplantation epiblast cells.
The adaptor protein Numb was initially identified in Drosophila as a critical cell fate determinant, where loss of Numb and its homolog Numb-like results in the loss of neural progenitors, indicating that the presence of Numb is essential for maintaining the progenitors during the initial progenitor versus neural fate decision.
Recent studies from our group and others have shown that the dynamical behavior of p53 encodes critical cell-fate decisions [ 23, 39]; hence, understanding how perturbations of p53 and key repair proteins will provide new and important insights for the treatment of tumors with different genetic profiles and repair deficiencies.
These data indicate the putative binding sites and the identity of transcription factors that may be responsible for the BCR-mediated co-regulation of the most critical cell-fate decision-making genes, and it is intriguing that these are the only predicted B cell-specific transcription factor binding sites that are found in the promoters of all five genes.
Interestingly, Hes1 is not essential for maintenance of the stem cell state of ES cells, but Hes1 levels at the time of induction of differentiation are critical for the fate choice: Hes1-high cells are prone to the mesodermal fate and Hes1-low cells are prone to the neuroectodermal fate (Kobayashi et al. 2009).
Italy's size makes its fate critical to the debate over the euro's future.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com