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The reliability of docking results can be further boosted when combined with functional studies such as thermodynamic mutant cycle analysis, which provide critical constrains for computation and validation.
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Together with knowledge about critical dose constrains for relevant organs at risk, our data can be used to guide modern radiation therapy towards genitourinary-sparing techniques to avoid future toxicity.
This study contributes a rigorous diagnostic assessment of state-of-the-art multiobjective evolutionary algorithms (MOEAs) and highlights key advances that the water resources field can exploit to better discover the critical tradeoffs constraining our systems.
It is critical to constrain how this kind of soil behaves during coseismic ground shaking, as well as the effects of dynamic loading on shear strength parameters after shaking.
In addition to the potential influence of the terrigenous (non-ash) sedimentary component, the amount of ash in the sediment column is critical to constrain, not only for the determination of absolute geochemical fluxes into the "Subduction Factory" but also in order to determine how much of the input is "recycled" from the arc itself.
Memory conflict is a critical problem that constrains the throughput of the semi-parallel decoder.
However, when early closure is the result of a taboo topic, which constrains critical reflection, there is reason for caution.
Success in algebra during the middle grades is widely recognized to be a critical gatekeeper that constrains students' decisions about whether to pursue further educational opportunities in Science, Technology, Engineering, and Mathematics (STEM) fields (Adelman 2006).
The findings clearly suggest that the use of the religio-cultural thesis as a conceptual framework in this paper was most appropriate in drawing attention to the Islamic religion as a critical factor that constrains access and use of modern maternal health services among Muslim women [ 16].
He wrote that federal authorities were "constraining" critical terrorism investigations in New York and said the federal government "is doing less than it is lawfully entitled to protect New York City," concluding that "the city is less safe as a result".
Traditional hemodynamic monitoring in critical care is constrained by the ease and frequency at which measurements can be made and taken.
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