Sentence examples for critical consequences on from inspiring English sources
Combined with our observations in Dnmt3L A/A animals, this supports a dosage effect and that despite the presence of one copy of Dnmt3L, the D124A mutation has critical consequences on gametogenesis and phenocopies complete absence of Dnmt3L protein.
Tumor-dependent triggering of the angiogenic switch has critical consequences on tumor progression which extends from an increased nutrient supply and relies instead on the ability of the tumor to hijack the host immune response for the generation of a local immunoprivileged microenvironment.
This outcome could resemble high-fat men consumers, with critical consequences on semen quality and therein on male fertility.
It has critical consequences on social and occupational participation and causes serious disability.
The magnitude of NKT cell activation and expansion may have critical consequences on the efficacy of NKT cell therapies.
RFP2 downregulation (Supplementary Material, Fig. S2E) caused almost the doubling of α-sarcoglycan mutant level (Fig. 5A), demonstrating that the loss of RFP2 has critical consequences on the disposal of V247M mutant.
Consequently, when hazard to human(s) is concerned a common design target is to protect the system from single points of failure (SPOF) which means that no failure mode caused by a single event, concern, or error has a critical consequence on the system.
Taken together, these observations suggest two distinct roles for PHR proteins in learning and memory: 1) a role in the development of neurons, which has a critical consequence on short-term learning later in adulthood, and 2) a role in regulating the consolidation of long-term memories specifically in adulthood.
The findings emphasize the importance of early tumor detection and the critical consequence of the inter-dosing interval on therapeutic efficacy, as supported by similar research involving chemotherapy.
The most critical consequence of the lack of data on the efficiency of the extraction methods of Roman paint binders, and the possible influence of microbial contamination, is the difficulty in knowing at this point whether some results are inaccurate, and to what extent, fomenting an overall uncertainty on Roman wall painting techniques.
The effects of this substitution on post-cultivation fallows are unknown, but may have critical consequences for biodiversity and forest regeneration.
