Sentence examples for critical cell type from inspiring English sources

Macrophages represent a critical cell type in host defense, development and homeostasis.

It is well-established that CNS-resident microglia serve as a critical cell type for host defense, capable of initiating and regulating rapid responses against infections [2].

Thus, the chance engagement of molecule A with molecule B within a critical cell type cell or the chance cognate engagement of a critical cell type (such as a naïve CD4+ T cell) with an antigen presenting cell (APC) could trigger the development of lupus.

This study examined the impact of a 12-amino acid IDR peptide, IDR-1002, in pro-inflammatory cytokine interleukin (IL -1β-induced responses IL -1β-inducedbroblasts, a crIL -1β-inducedpe in the pathogenesis of inflammatoresponsestin.

Recent studies in mice suggest cooperativity between SCLC cells with epithelial and neuroendocrine characteristics, and that the latter are the critical cell type for metastatic formation in SCLC, at least in this mouse model (Calbo et al, 2011).

However, given that in the mouse model of SCLC, neuroendocrine features are important in tumour progression and metastasis (Calbo et al, 2011), there may be cooperativity between epithelial and neuroendocrine cells, with the latter as the critical cell type for metastasis formation (Calbo et al, 2011).

Trynka, G. et al. Chromatin marks identify critical cell types for fine mapping complex trait variants.

Conclusions regarding critical cell types will become more robust as more loci are discovered.

Besides cirrhosis, several other diseases are thought, though not yet proved, to be caused by telomere shortening and the depletion of critical cell types.

Soumya Raychaudhuri and colleagues report a broadly applicable method that uses chromatin marks, specifically H3K4me3, to identify critical cell types to fine map complex trait variants.

Immune cells are now appreciated to have powerful influences on critical cell types required for regeneration success.