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These are critical attributes for pericyte identification (Armulik et al., 2011).
Historically, patient- and tumor-related factors such as age, histology, tumor volume and stage have been critical attributes for predicting patient outcome and overall survival for cervical cancer.
Sensitivity (the proportion of cases of a health-related event detected by a system) and positive predictive value (the proportion of detected cases that truly have the health-related event) are critical attributes for most surveillance systems but were deemed to be less important for this particular type of system where vaccination is the outcome of interest, and data are captured electronically.
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Fast-twitch fibres tire easily but are good for rapid muscle contraction over short distances – a critical attribute for sprinting.
In addition to the abovementioned attributes, function is another critical attribute for mAb-based biologics.
In the design of these components the low cycle fatigue strength is a critical attribute for material selection.
Reliability has long been recognized as a critical attribute for space systems, and potential causes of on-orbit failures are carefully sought for identification and elimination through various types of testing prior to launch.
Reflection on professional experience is increasingly accepted as a critical attribute for health care practice; however, evidence that it has a positive impact on performance remains scarce.
Palatability and ease of swallowing are also considered as critical attribute for the acceptability of medicines intended for children, who possess distinct preferences and swallowing abilities than other subsets of the population.
Pragmatically, the most critical attribute for a biomarker is not that it diagnoses Parkinson disease early, before motor features appear, but rather that it reflects a pathogenetic process and progression of the disease against which potential disease-modifying agents may be judged.
Details and timing are critical attributes of a good engineer.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com