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Finally, if there was no crossing and the rate function was completely above the criterion, the response was defined as non-selective.
Using the less conservative 30% reduction criterion, the response rate increased to 78%.
Using this criterion, the response rate was 8.5% in the placebo group, 35.3% in the 10 mg group, 36% in the 15 mg group, and 38.6% in the 20 mg group.
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In line with the EULAR criteria, the response criteria can be applied only to those patients with an initial DAS28 >3.2 in the first trimester (n = 84).
On the basis of immune-related response criteria, the response rate (CR + PR) was 12%95%5% confidence interval [CI], 5%-25%), whereas 29% had SD (95% CI, 18%-44%).
However, because of some limitations of the WHO criteria, the Response Evaluation Criteria in Solid Tumors (RECIST) was introduced in 2000.
Response to bevacizumab, which exerts an anti-angiogenic action, may be inadequately assessed by traditional size-based radiologic criteria, the Response Evaluation Criteria In Solid Tumours (RECIST) (Therasse et al, 2000; Eisenhauer et al, 2009).
The main outcome criterion was the response rate after 14 days.
The primary outcome criterion was the response rate after 14 days of therapy.
The histological criteria for the response of CRT were as follows (Japanese Society for Esophageal Diseases, 1999).
These criteria combine the response observed in skin, lymph nodes, viscera and blood to a global response category.
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