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An additional 15 catch trials were interleaved randomly, presenting stimuli identical to those used in the criterion phase.
As in the equivalent noise task, there were an additional 15 catch trials, which presented stimuli used in the criterion phase.
Each equivalent noise and motion coherence task consisted of three levels: a combined demonstration and criterion phase ('level 1'), a practice phase ('level 2'), and a threshold estimation phase ('level 3'level
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Primary objectives are determination of the optimal doses for pazopanib (phase I) and the overall response rate according to RECIST criteria (phase II).
Four investigators (CC, LC, KL and KM) screened titles and abstracts for relevance in two phases based on the inclusion criteria: phase one eliminated all clearly irrelevant studies, phase two applied all inclusion/exclusion criteria listed above for the remaining studies.
Dose escalation was according to the standard phase I criteria.
Image analysis is applied based on two new algorithms: concentric expansion for strip delineation and overflow criterion for phase segmentation.
Based on a consistency analysis for each criterion following phase II, the wording of the CRED evaluation criteria was optimized if consistency (see consistency analysis below) was below 50%%.
Two participants failed to meet criterion in Phase 4 within the ten blocks available, one participant approaching criterion in the final block, and one near chance.
Aβ deposits were highly abundant in all Arctic AD patients' cerebellum, but they were few in brain stem nuclei the criterion for phase 4.
Phase B participants (n = 9) were recruited using the same criteria as Phase A. Additional inclusion criteria for the Phase B smoking cessation trial were being a current smoker who smoked at least 10 cigarettes/day, no reported period of smoking abstinence greater than three months in the prior year, no history of hypersensitivity to nicotine or adhesives, and motivation to quit smoking.
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