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It could also represent a direct criterion of efficacy in evaluation of vector control strategies.
Each treatment arm will be compared to theoretical rates using a design with one single stage (no interim analysis of the primary criterion of efficacy).
Presented with the evidence from the literature through May 2009 (Table 3), the panel of experts expressed concern (score around 50%) regarding the ability of aerosolized measles vaccines to satisfy the criterion of efficacy.
The primary criterion of efficacy was defined as survival during the 36-month double-blind period of the study (1095 days included) or until the administrative cut-off date (November 30, 2004 included) whichever came first.
The primary criterion of efficacy in the confirmatory analysis was the absolute change in the NIS-LL+7 score expressed as normal deviates (nds from percentiles correcting for age and other applicable variables) between baseline (mean of visit during weeks 1 and 2 or last available value before randomization) and end point (mean of weeks 191 and 192 or last available value after randomization).
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The four criteria of efficacy, safety, cost and convenience are considered while selecting a P-Drug.
Furthermore, we incorporated the three criteria of efficacy identified by Rueda and colleagues [ 15].
Beyond recognition, target accessibility and tumor infiltration, mechanisms, and efficacy of killing are other criteria of efficacy to be considered.
The priority problems of current health care systems are: a shortage of available resources to meet general growing health demands; providing comparison tools; developing health care projects and technologies according to criteria of efficacy and convenience; and identifying a scale of priorities to guide the use of public resources.
Response rates for influenza vaccination varied between 40 and 80% for breast (Brydak et al, 2001; Vilar-Compte et al, 2006), colorectal (Puthillath et al, 2011) and lung cancer (Anderson et al, 1999): when seroconversion rates were the criteria of efficacy, response rate was around 40%, and when seroprotection rate was chosen, the rates increased to 80% (Pollyea et al, 2010).
Setting an arbitrarily high criterion of clinical efficacy for new psoriasis treatments will likely limit the development and approval of useful treatments.
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