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The Disability scale was found suitable as an external criterion of change in the construct being measured, r being 0.51 (Table 4).
fastSTRUCTURE was executed with a convergence criterion of change in the per-genotype log-marginal likelihood lower bound |Δℰ| < 10−8.
In the present study, the predictive validity of the SF-12 and EDQOL administered at baseline was tested against the criterion of change in DOR and WSAS scores from baseline to post-treatment.
Differences did exist, however, in the relative ranking of generic HRQL measures according to the external clinical criterion of change used (Tables 6, 7, 8; Figures 1, 2, 3).
With a 20% change in firing rate as a criterion of change (LeBeau et al., 2001, Burger and Pollak, 2001; Park et al., 2008), 14% (7/49) V FRAs decreased in firing rate while 35% (17/49) increased.
Broadly, these are classified as either anchor-based, where an external criterion of change is used to compare the observed changes in scores, or distribution-based, where the observed change is compared to the statistical properties of the sample or instrument [ 20].
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A limitation with our study is that we did not control for recall bias and we did not compare the changes with any criterion measure of change [ 18, 19].
Further research using external criteria of change is warranted.
The greater responsiveness of the KCCQ was consistent across all four responsiveness indices used and across the three external clinical criteria of change.
Instruments should be administered longitudinally before and after treatment known to improve PF, and health transition questions should be included as external criteria of change (26).
The ACR criteria are a dichotomized measure of change, whilst the EULAR criteria include change as well as the level of disease activity reached.
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Justyna Jupowicz-Kozak
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