Patients had active disease that was consistent with the criteria of activity: (1) ≥ six joints were swollen; (2) ≥ six joints were tender; and (3) two of the following three criteria were satisfied: (a) on the day of the visit, morning stiffness lasted more than 45 minutes; (b) erythrocyte sedimentation rate (ESR) ≥28 mm/h; and (c) C-reactive protein (CRP) ≥20 mg/dl.
Of these three compound classes, only compounds represented by scaffold C fulfilled the final probe criteria of activity (<1 μM) and selective inhibition of NOD1-induced NF-κB activation.
Clinical criteria of activity and efficacy were ORR, PFS and OS.
Clinical criteria of activity and efficacy were ORR, PFS, and OS: ORR, evaluated according to RECIST criteria [ 27] and PFS and OS, evaluated using the Kaplan-Meier method [ 28].
Measurement of the rate of oxygen utilization and carbon dioxide production by activated sludge sewage mixtures has become prominent in recent years as a criterion of sludge activity and other characteristics of the activated sludge methods of sewage treatment (Sawyer and Nichols 1939; Genc and Yonsel 2007).
According to the report of the American National Cancer Institute (NCI), the criterion of anticancer activity for the crude extracts of herbs is an IC50<30 μg/ml [ 32].
The participants in this study, family caregivers, both users and non-users all most frequently cited the quality criterion of an activity programme, suitable for the individual abilities of dementia patients.
Thus, the criterion of "normal activities of daily living" has been revised to a less stringent one allowing for discrete IADL deficits in patients with MCI.
For high vs. low physical activity level, two studies used the cut-point of 3 or more times per week [ 133, 145], one used 2 times or more per week [ 142], one used the criterion of 4 activities per week vs. none [ 141], one used > =2 vs. <2 miles walking/day [ 137], and the remaining four studies used other definitions related to both frequency and intensity [ 148, 150, 156].
