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Isolated 46-mers from both aaRS classes bind tightly to ATP (KD = 10-65 μM), as has been observed for structurally homologous 45-51 residue fragments isolated from a variety of nucleotide-binding proteins [ 67- 71] containing the Walker-A motif and, by this criterion, may prove to be distant relatives of the Class I aaRS [ 39].
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For direct seeding in N-deficient farming systems, landscape criteria may prove useful for minimizing production risks by identifying field areas with lower SP rates.
I don't believe that #1 is true (although other criteria may prove them incompetent), and that leaves us with #2.
Indeed, due to considerable necrosis even at diagnosis, VACT criteria may prove less efficient in aggressive lymphoma subtypes such as diffuse large B-cell lymphoma or Burkitt lymphoma even though rim enhancement due to persistent peripheral vascularization is likely.
Our study suggests that structural and functional imaging markers can improve diagnostic accuracy when supplementing clinical criteria and may prove useful in future iterations of criteria.
However, the uncertainties underlying the use of expert opinion to interpret the quality of experimental evidence or to establish weights for criterion in MCDA approaches may prove to have a critical effect on the resultant assessment [11].
It is necessary to review from time to time the diagnostic criteria for particular syndromes, otherwise they may prove to be too restrictive.
Recently endorsed by the International Expert Committee [ 13] and the American Diabetes Association as a diagnostic criterion for diabetes mellitus [ 14], haemoglobin A1c may prove useful in categorising inpatients [ 15].
Thus, face validity may prove to be an unrealistic criterion for some symptoms of the disease such as motor and cognitive deficits or emotional changes.
Thus, the quantitative criterion is not entirely satisfactory, and a qualitative one may prove more appropriate.
This may prove disastrous.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com