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The only other criterion for entering this study was that both paraffin-embedded and frozen tumor tissue was present.
The criterion for entering and exiting the variables in the model was, respectively, being of P value > 0.2 and P value < 0.4.
The criterion for entering the variable in the model was to produce a p value less than 0.20 in bivariate analysis.
A significance level of 5% in the univariate analysis was chosen as the criterion for entering variables (SBR grade, nodal status, ER, uPA, PAi-1, TK and TGF β1) (not shown).
A stepwise backward elimination process has been used and the final models only included variables providing a significant explanation of outcomes, in which the criterion for entering and exiting in the model was, respectively, of P value > 0.2 and P value < 0.4.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com