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The fit was carried out in an Excel ® spreadsheet using the Solver tool, and the sum of squares (SSQ) as goodness of fit criterion (details can be found in Rabinovich and Zubillaga, 2012 ).
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This generated scepticism about possible sequence assembly and annotation mistakes and prompted a more stringent search criterion, detailed below.
Seven genes of the DosR regulon which showed high experimental variability were filtered prior to analysis according to a criterion detailed in the methods.
Because the rule is abstract and can contain meta-criteria, details about them must be present.
Third, the survey is systematically shortened according to pre-established criteria (details below) and compared once again to the published long-form structure.
The scoring criteria details are shown in Table 1.
The quality criteria details are presented as an appendix [see Additional File 2].
Seven trials met the inclusion criteria (details of study flow are given in Figure 1).
The other 4 trials [ 25, 36, 55, 59] used the modified diagnosis criteria (details in Table 1).
For each study identified that met the selection criteria, details on study design, study population characteristics, intervention, outcome measures and study quality were extracted.
GBD 2010 included all studies from these reviews after applying additional exclusion criteria (details of the search strategy are available in Additional file 4, supplementary materials).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com