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Clearly the uses of second criterion are rather limited in patients with isolated hypophysitis IgG4-related disease such as in this patient.
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As the MCDC coverage preservation criterion is rather complex, we derive them in two steps.
Our criterion is rather stringent, in the sense it requires a perfect match of each R I with the MIPS, KEGG or GO categorization.
47 Although we recognise that this criterion is rather arbitrary, the lower confidence interval calculated in the present review, a mean difference of –2.27 points in HRSD scores, does not cross this threshold.
While these criteria are rather rough and simple, the issue of reproducibility and anatomical precision becomes already more challenging when MRI (or less frequently CT) is used to assess the slow reduction in grey matter taking place in dementia over time [3].
Currently used criteria are rather restrictive for a condition that is quite polymorphic in nature.
These criteria are rather stringent, but we found that they reliably classify cells pairs.
This shows that our selection criteria are rather stringent, increasing the probability that identified candidate genes are involved in OFCs.
Further, if applicable and also considering that the clinical criteria are rather limited, in a larger family collection, this data could be considered.
Even if thermo coherence correlations coefficients to the convergence criteria are rather moderate until low, there is face validity that thermal comfort influence not only quality of life and a feeling of coherence [ 15].
Since patients who met the inclusion criteria were rather rare and negative results were obtained in the first group of the total eight patients, it was decided to discontinue this study after the first data analysis.
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