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Of 298 consecutive patients enrolled from April 2015 to September 2016, 15 patients (median age 71 yrs. ± 8.89; tPSA 13.5 ng/ml ± 4.3) fulfilled the inclusion criteria: negative mpMRI (PI-RADS v.2 < 3).
Complete remission was defined according to the International Myeloma Working Group criteria: negative immunofixation with disappearance of any plasma cytomas and >5% plasma cells in the bone marrow.
In the 11 patients that satisfied the ConCerv criteria (negative margins and LVSI on conization) and 14 patients that met the GOG-278 inclusion criteria (negative lateral margins and depth of invasion ≤ 10 mm on conization), the rate of PMI was 0%.
All PCa patients were submitted to radical prostatectomy, and were selected by using the following criteria: negative X-rays and bone scan analyses, and rectal examination compatible with organ confined cancer.
EGFR, p-EGFRtyr1068 and p-EGFRtyr1173 were interpreted according to the follow scoring criteria: negative, no reaction; 1+, 2+ or 3+, if neoplastic cells displayed a weak, moderate or strong plasmamembrane immunostaining, respectively.
Cells were released for patient administration after meeting the following criteria: negative for mycoplasma via polymerase chain reaction, ≥ 70% cell viability, growth assay via colony forming unit-fibroblasts assay, positive for CD105 (> 80%) and negative for CD45 by flow cytometry, and no growth of bacteria.
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Again, these standard performance statistics calculate identification with respect to the criterion positive and criterion negative 'opportunities' in each study, rather than the total sample n.
When the studies that contained full criterion positive and criterion negative information are combined and these standard equations applied, the percent of criterion positives that are test positive (sensitivity) is 84%, and the percent of criterion negatives that are test negative (specificity) is 74%.
Weighting n by observed prevalence (or 1-prevalence for specificity) instead provides the number of criterion positive and criterion negative cases for each study and allows for the standard calculation of sensitivity and specificity.
Table 3 Binary classification characteristics of 68Ga-DOTANOC CS diagnosis (JMHW criteria) Positive Negative DOTANOC diagnosis Positive 3 0 3 Negative 0 16 16 3 16 19.
Criteria for negative morphologically abnormal discs may be valuable for excluding discs from further treatment and examination.
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