There was no pattern of repeated QC failure by a single subject sampled on more than one occasion, neither was there correlation of failure with differential or % non-epithelial contamination. 1 The 233 samples were assessed by the established QC criteria and all those failing one or more were classified by which QC criteria were failed.
In addition, a sensitivity analysis is conducted varying the percentage of by how much the criteria are failed between 85% and 95%.
Assuming that the vB criterion is failed by less than 5% (instead of 10%) reveals that 1,2-dichloro-4- trichloromethyl benzene would not be considered as a borderline chemical anymore since its estimated BCF (4,572 L kg-1,2-dichloro-4- trichloromethyl benzenee criterion for vB, 5,000 L kg-1,2-dichloro-4- trichloromethyl benzene
If the vB criterion may be failed by up to 15% instead, an additional substance 1-chloro-2- chlorodiphenylmethyl benzenee, CAS 42074-68-0) has to be considered more closely.
The final results of the analysis indicate that the there is approximately 95% confidence that the regulatory criteria under consideration would be failed given the high level of physical data provided.
If any of these criteria were not met, then the plate was failed and repeated.
He felt that the SIRS criteria were too vague, failed to include vital parameters, failed to consider the site of infection and failed to usefully assess severity of illness.
Any recommendation that does not clearly communicate what to do (i.e., it fails executability criteria) or when to do it (i.e., fails decidability criteria) is not fully ready for implementation.
Yet none – even by his own original criteria – was ultimately to fail more abjectly.
The predictive validity of Berlin criteria was similarly marginal and failed to identify three distinct mortality classes with a mortality of 18% in mild versus 19% in moderate ARDS.
