In addition, the learner must come to see the new explanation as intelligible (easily understood), plausible (credible), and fruitful (useful for explaining other phenomena), drawing their criteria from studies of what causes scientific communities to adopt a new theory.
The wide range in rates reflects, at least in part, differences in diagnostic criteria used from study to study.
Patients included in the study were randomly sampled from all patients meeting inclusion/exclusion criteria from each study investigator's site.
In the study by Jensen et al., some patients without infection were also included [13]; therefore, we only included patients with severe sepsis or septic shock that fulfilled our inclusion criteria from this study.
There was no modification in design or eligibility criteria from the study protocol available at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761388/.nih.gov/pmc/articles/PMC2761388/
The number of cases that met the inclusion criteria and the performance of the criteria from each study are shown in Table 4.
The patients were excluded, due to any of the exclusion criteria, from the study following critical review of their medical charts.
Age less than 16 years, pregnancy, neurobrucellosis, previous history of brucellosis and antimicrobial therapy and discontinuation of the therapy for any reason (allergy to any of the drugs, death, adverse reactions) were exclusion criteria from the study.
Current pregnancy, diabetes, smoking and onicophagic habitus, presence of anti-phospholipid antibodies, and assumption of beta blockers, all conditions that may influence the NVC pattern, were considered as exclusion criteria from the study.
