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On the basis of optimization criteria, composition of optimized formulation F0 (Methocel K100LV = 77.98 mg and Carbopol 934 = 82.02 mg) was determined by statistical analysis.
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For examples, Worning et al. [ 30] predicted the location of oriC using biased distribution of all oligonucleotides up to 8 bp, and Mackiewicz et al. [ 31] use three criteria – composition skew, location of dnaA gene, and distribution of DnaA box-like sequences – for oriC prediction.
Other questions elicited information on clear provision for NEC membership criteria; composition and functions of NECs; and whether all research institutions were required to adopt policy regarding research ethics.
Leclercq et al. have previously shown that both the weights and threshold criteria influence the composition of the microsatellites detected (see also supporting information, Figure S1 for the differential screening results from the present study).
The primary design criterion for the composition of the MA-TGMs was the attachment of hydrophobic cross-linkable groups that serve the dual purpose of decreasing the LCST and allowing for chemical cross-linking of the MA-TGM chains.
They use term bounding functions as a parametric notion of safety, which can be instantiated with syntactic, semantic or combined safety criteria; this empowers us to generalize and integrate many other notions of safety from the literature, and modular composition of criteria makes future extensions easy.
The proposed verification methodology relies on an abstract modeling of the functional behavior of the blocks and a set of consistency criteria defined over the composition of these abstract models.
Based on the success of recovery of the true model in each simulation (Numbermatched; see the ' Accuracy' part), we employed the χ2 homogeneity test [ 42] to compare the four criteria in terms of the composition of selected models.
High-stringency criteria are based on the composition of off-target cleavage sites observed in large-scale analyses conducted in animals (Chiu et al. 2013; Yang et al. 2013) and define potential off-target sites as those with (i) perfect matches (zero mismatches) to the seed sequence or (ii) one mismatch in the seed sequence when there are only one or zero mismatches in the distal sequence.
To calculate the execution time of stakeholders' requests, the proposed fitness function is a composition of three important criteria which are CPU utilization, turn-around time and waiting time.
All were entered into the model, and a stepwise selection process combined with finding a parsimonious minimum of the Akaike and Schwarz model information criteria [ 19] resulted in the final composition of the model.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com