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Therapeutic effect was graded according to WHO criteria: complete remission (CR), tumor completely disappeared; partial remission (PR), more than 50% tumor shrinkage; stable disease (SD), tumor grows or shrinks no more than 25% and no new lesion foci appear; and progressive disease (PD), tumor grows more than 25% or new lesion foci appear.
For analysis of mitochondrial clustering, cells were scored based on the following criteria: Complete clustering, nearly all mitochondria in the cell were closely juxtaposed; Partial clustering, some of mitochondria in the cell were juxtaposed; No clustering, mitochondria are scattered and not juxtaposed.
Protection was also defined by very stringent criteria: complete lack of evidence of infection, by any method of detection at any of the time points analyzed, including a systemic post-mortem analysis.
Based on these criteria, complete curves were obtained for only 6.72% of all records (1539/22912).
Patients who meet the inclusion criteria, complete the baseline questionnaire and consent to the trial will be included.
Efficacy was assessed according to the WHO criteria (complete remission (CR), partial remission (PR), stable disease and progressive disease (PD)), including RR (CR and PR) and PFS.
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During the process the students videoed the scenario for peer assessment, developed marking criteria, completed an online survey and participated in a focus group.
In order to facilitate the procedure, a group decision support system (GDSS) was fed by four evaluation matrices given by the team, who defined a common set of criteria completed by an overall direct evaluation.
The ATP cohort included participants that met all eligibility criteria, completed the vaccination course and contributed to follow-up time during the evaluation period.
Those who met the eligibility criteria completed a CASI.
From these, 188 adolescents met the inclusion criteria, completed the baseline measurement (T1), and were randomized.
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CEO of Professional Science Editing for Scientists @ prosciediting.com