Sentence examples for crib region from inspiring English sources

As the CRIB region of human and zebrafish PAKs are essentially identical, we can conclude that Chp is indeed able to act upstream of PAKs in zebrafish.

To this aim, we measured Rac1 activity by an affinity assay in which Rac1-GTP was pulled down from lysates of adherent ECs incubated with a GST fused to the Cdc42/Rac Interactive Binding (CRIB) region of the Rac1-GTP effector p21-activated kinase1 (GST-CRIB).

The domain structure of Ack1 is unique among cytosolic kinases and contains an SH3 domain C-terminal to the kinase domain, a Cdc42/Rac interactive binding (CRIB) module, and a huge polyproline region.

MLK3 protein is composed by a Src-homology-3 (SH3) domain, located at the amino terminus of the protein, followed by a kinase domain, a leucine-zipper region, a Cdc42/RAC interacting binding motif (CRIB) and a Proline/Serine/Threonine-rich (P/S/T-rich) carboxy terminal domain [ 1- 4].

The SH3 domain of MLK3 can bind a proline residue in a region between the leucine zipper and the CRIB motif resulting in auto-inhibition (6).

As already mentioned, the boundaries of the GBD region remain poorly defined and while a CRIB-like (Cdc and Rac interactive binding) region has been described in mammalian DRF [ 37], such motif cannot be identified in any other formin, whether regulated by Rho GTPases or not.

Although there is considerable variation in the motifs that different effectors use to bind Rho GTPases, a number of effectors share consensus binding regions such as the Cdc42/Rac-interactive-binding (CRIB) domain found in Wiskott Aldrich syndrome protein (WASP) and P21-activated kinase (PAK).

CUFF115357.1 was located between polyubiquitin genes (UBQ) and the ROP interacting CRIB (Cdc42/Rac-interactive binding) motif protein (RIC) on chromosome 4, and the syntenic region in rice chromosome 2 was identified by aligning the genome sequence with the rice genome (International Rice Genome Sequencing Project Build 5.0 pseudomolecules).

In control BLM cells, CRIB co-localized with paxillin in several serial z-sections; some CRIB-positive adhesions formed clusters/rosettes in the cell periphery and cell central region (Fig. 8B).

I have tried to picture a crib in my crib.

A. Cord log storage crib.