Credible case studies – exposure to what happened, how it happened and what to look for?
At the Center for Nanotoxicology at Pacific Northwest National Laboratory, researchers combined two models to enhance the ability to extrapolate between in vitro and in vivo results to help improve the design of future studies and derive credible human occupational exposure limits for ENMs.
Tetrachlorvinphos is a common ingredient in flea and tick products and a credible source of exposure in New York City, where pets tend to stay indoors and living spaces are smaller.
Foster & Agzarian (2007) suggest reporting results to individuals for substances for which "there is credible evidence linking exposure with adverse health effects in the human population" but not for those substances for which "human health risks and intervention levels are unknown".
The present work provides a methodology to address this type of limitation by applying multiple imputation methods to extract the maximum information from available data, making it possible to use incompletely known residential data to put credible bounds on exposure metrics.
Predicted water concentrations from our linked modeling systems provide more credible drinking water exposure concentrations for public water systems in the six municipal water districts compared with other public and private water sources for which geocoded well locations or well depths were not available.
A separate review of medical literature by the Australia Institute debunked the fear that wind power damaged people's health, finding "no credible evidence" directly linking exposure to turbines with negative health effects.
In 1999, following multiple bioterrorist threats (38) (Epi-Aid 1999-25), antibiotic prophylaxis was recommended in cases with known or credible risk for direct exposure.
For example, the 95% credible interval for high exposure to NO2 in group 1 is > 0 (0.86, 0.86), indicating that this group was characterized by subjects who are more likely to have high exposure to NO2 than the overall population.
This community is also concerned that the research on the possible human health effects of toxicant exposure be credible within the scientific community because negotiations with industry regarding remediation are still under way.
